Trends from the Trenches Podcast

CEO Andrew Hopkins on Exscientia’s AI-Driven Approach to Modern Drug Discovery

February 28, 2023

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The steel industry is not a common birthplace of biotech companies, but Andrew Hopkins traces the ideas that became Exscientia back to his time there. New technologies and new processes replaced nearly 90% of the steel workforce, and Hopkins kept those market lessons. He says, “When I ended up in pharma and biotech, I had a very different perception of the power of commerce and markets and what they can potentially drive, and the power of new technology to position oneself in those markets.”

In this episode, Andrew Hopkins, CEO and Executive Director of Exscientia, speaks with host Stan Gloss of BioTeam about his desire to fundamentally change drug creation mechanics and processes with technology, his graduate experience working in human immunodeficiency virus drug design at Oxford University, and his stint at Pfizer. He also discusses Exscientia’s machine learning-based and model-driven approach to drug design, the connection between knowledge and efficiency in drug optimization projects, and its fourth platform-designed drug launch into the clinic.


Andrew Hopkins, CEO and Executive Director, Exscientia
Andrew is among the most distinguished and cited scientists in modern drug discovery. As founder and CEO of Exscientia, he invented and championed an automated and algorithmic drug design and discovery approach. Before that, he spent 14 years at Pfizer and in academia, pioneering cutting-edge projects using data mining and machine learning in the pharmaceutical industry. His papers, published in Nature journals, are widely considered pivotal points in the new paradigm of modern drug discovery.


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Host Bio

Stan Gloss

As co-founder and Evangelist of BioTeam, Stan Gloss has been working to tell the stories of the intersection of science, data and technology since 2002. Gloss joined with fellow founding partners Bill Van Etten and Chris Dagdigian to form BioTeam in 2002 following his tenure in business development with AVAKI Corporation, a pioneer in global grid software solutions, and Blackstone Computing, a computing and IT consulting company for scientists, Gloss led the sales initiative that launched the company in the life sciences market. Gloss earned his MS at the University of Buffalo and was a department chairman and faculty member at Quinnipiac University.

A life science IT consulting firm at the intersection of science, data, and technology, BioTeam builds innovative scientific data ecosystems that close the gap between what scientists want to do with data—and what they can do. Learn more at www.bioteam.net.



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Meet the Host

Eleanor Howe

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Eleanor has been working at the cutting edge of bioinformatics for over 20 years. As founder of Diamond Age, she led the company’s evolution from a small, project-based service provider to a full-fledged consultancy that works closely with clients to tackle their most difficult research challenges. Trained as a computational biologist, Eleanor has deep expertise in transcriptional profiling as well as drug discovery and development. She earned her doctorate degree in bioinformatics from Oxford University and spent years in biomedical research at The Institute for Genomic Research, Dana-Farber Cancer Institute, and The Broad Institute.


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