Data Storage Infrastructure Image

Is the burden of managing your data growing larger every day? Do you have a scalable and robust data storage infrastructure in place that allows proper storage, processing, analyzing, and transferring of vast quantities of data according to your organization policies? Is your organization using new tools and analytical processes such as AI and deep learning that stress your supporting data storage infrastructure beyond the expectations of system designers? Managing data has become a prevalent issue in the life sciences industry. Organizations are spending millions on systems and platforms to manage, store, and transfer many types of data (e.g., experimental, operational, clinical) from many different disparate sources. The role of data engineering is critical in orchestrating, configuring, managing, and scaling solutions to manage the data bloat problem. The Data Storage Infrastructure track presents in-depth case studies from leading life sciences organizations who are implementing solutions to address data storage and computing requirements. We will discuss system design including capacity, performance, and availability.

Monday, September 20

7:30 am Registration Open
8:00 am Recommended Pre-Conference Workshops*

Cambridge Healthtech Institute is pleased to offer morning and afternoon pre-conference workshops on Monday, September 20, 2021. They are designed to be instructional, interactive and provide in-depth information on a specific topic. They allow for one-on-one interaction and provide a great way to explain more technical aspects that would otherwise not be covered during the main conference tracks that take place Tuesday-Wednesday. 

*Separate registration required. See Workshop page for details.

9:30 am Break
9:45 am Recommended Pre-Conference Workshops*
11:15 am Enjoy Lunch on Your Own
12:45 pm Recommended Pre-Conference Workshops*
2:15 pm Break
2:30 pm Recommended Pre-Conference Workshops*
4:00 pm Session Break and Transition to Plenary Keynote

PLENARY KEYNOTE PROGRAM

4:15 pm Innovative Practices Awards – Winners Spotlight
4:20 pm PANEL DISCUSSION:

Pharma Executive Roundtable: Broadening the Data Ecosystem

Panel Moderator:
Lita Sands, Head, Life Sciences, Amazon Web Services

The Bio-IT World community employed creativity, problem solving, and technical ingenuity to weather 2020 and never was the work more important. Meanwhile, digitization has been broadening the horizons of new possibilities and initiatives that are driving innovation in the life sciences sector. While over the past year many pharmaceutical companies have seen an acceleration of digital transformation, there are still many that are unsure what to expect going forward. Digital transformation is now a strategic imperative, not a buzzword. Join our Pharma Executive Roundtable to discover how biopharma companies are broadening their digital strategies and capabilities to develop products and services to scale, streamline operations, and drive innovation in life sciences R&D. 

Panelists:
Ramesh V. Durvasula, PhD, Vice President & Information Officer, Research Labs, Eli Lilly & Co.
Michael Montello, Senior Vice President, R&D Tech, GlaxoSmithKline
Bryn Roberts, PhD, Senior Vice President & Global Head of Data Services, Roche
Holly Soares, PhD, Vice President & Head, Precision Medicine, Pfizer Inc.
Lihua Yu, Chief Data Officer, FogPharma
5:45 pm Welcome Reception in the Exhibit Hall with Poster Viewing
7:00 pm Close of Day

Tuesday, September 21

7:00 am Registration Open and Morning Coffee

DATA STORAGE PLATFORMS & RESOURCES

8:00 am Organizer's Remarks

Cindy Crowninshield, Executive Event Director, Bio-IT World Conference & Expo

8:10 am

Genomic Data Lakes: Research Data Storage at The Jackson Laboratory

William S. Sanders, Manager of Advanced Cyberinfrastructure, The Jackson Laboratory

At The Jackson Laboratory (JAX), the increased volume of research data generation, coupled with institutional culture, have led to the establishment of a multi-tiered research storage architecture to help meet these needs. This architecture and its associated policies were designed to stabilize and minimize the financial costs required to meet unconstrained research demand for increased research storage capacity. This talk provides an overview of the research computing environment at JAX, with a specific focus on the design decisions behind the capacity, performance, and availability choices of the research storage platforms with parallel and distributed computing systems, various data science and data analysis platforms, and data-generating scientific instrumentation.  

8:40 am

Bringing Scientific Data Management Systems Into the Cloud

Alex Bangs, Chief Information Officer, Vir Biotechnology Inc

Vir is a relatively young but fast-growing biotech company with a cloud-first approach to IT systems. As part of implementing a cloud-based Electronic Lab Notebook solution, we wanted to ensure all raw data and analysis for experiments would be captured in an immutable vault, similar to what the ELN offered. This is the realm of Scientific Data Management Systems, which have traditionally been installed on-premises. We ended up implementing a newer cloud-based solution that both gives us the long-term, scalable storage vault we were seeking while also providing a data lake with metadata that can be mined by Vir’s Data Science team in the future. This talk will re-walk our winding path to this destination, including the alternatives we considered and the requirements we developed, and share what we learned along the way.

9:10 am Coffee Break in the Exhibit Hall with Poster Viewing
Jeff Denworth, CMO and Co-founder, Executive, VAST Data
Liran Zvibel, CEO & Co-Founder, Executive, WekaIO

The cloud offers huge opportunity to scale research by leveraging public cloud compute elasticity. However, going all-in on the cloud is daunting at Petascale levels, especially with on-prem investments you want to leverage. We rarely see a complete lift-and-shift to the cloud; leading hybrid deployment to be the most effective use of resources.
 

This talk outlines strategies for getting the most from your cloud investment and leveraging existing on-prem storage infrastructure.

11:00 am Session Break and Transition to Luncheon Presentation
John Capello, Vice President, Product Strategy, Nasuni

Austin Radiological Association (ARA) said ‘Goodbye’ to their old file servers because they couldn’t scale fast enough to keep up with the millions of medical images being created every year across 17 ARA locations. They replaced the aging tech with a modern cloud solution that simplified every aspect of managing, sharing, and protecting files. On top of it, they cut their IT budget in half. With limitless capacity on-demand, access to medical images and other files from any location, and improved data protection, file storage is no longer an impediment to growth for ARA. Attend this session to learn how ARA is continuing to modernize its approach to storing, sharing, protecting, and managing unstructured data at scale – all through a unified solution that meets strict compliance and security requirements, while saving millions of dollars. 

12:00 pm Session Break and Transition to Exhibit Hall
12:15 pm Refreshment Break in the Exhibit Hall with Poster Viewing

PLENARY KEYNOTE PROGRAM

Michael Stapleton, PhD, Managing Director, Life Sciences, Accenture
1:15 pm

How Digital Evolution and an Attitudinal Revolution are Re-Shaping the Future of the Life Sciences Industry

Nimita Limaye, PhD, Research Vice President, Life Sciences R&D Strategy and Technology, IDC

The world has rapidly transitioned to a model of disaggregated care and decentralized clinical trials, with a heightened focus on patient-centricity. Digital resiliency has become the priority and discretionary spend on R&D platforms has been delayed. Federated-learning models are fueling co-innovation and GPU-powered transformer models are accelerating drug discovery. Technology is enabling access and equity. The borders between healthcare and life sciences are blurring and real-world data is being leveraged to drive a precision medicine strategy.

1:50 pm

All of Us Research Program – Seeking To Advance Precision Health for All Populations

Joshua Denny, MD, MS, CEO, All of Us Research Program, National Institutes of Health

The All of Us Research Program launched May 6, 2018 and currently has over 375,000 participants who have contributed biospecimens, health surveys, and a willingness to share their EHR. Participants are partners in the program and receive research results from data they contribute, including genetic ancestry and traits. In the future, participants will also receive health-related genomic results from whole genome sequencing. In May 2020, the program launched the beta version of the Researcher Workbench. Once researchers register and are approved to use the workbench, they can access individual-level data and a suite of tools to analyze these data. All of Us is committed to catalyzing a robust ecosystem of researchers and providing a rich dataset that drives discovery and improves health.

2:30 pm Refreshment Break in the Exhibit Hall with Poster Viewing

DATA STORAGE PLATFORMS & RESOURCES

3:00 pm

Chairperson's Remarks

Chris Dwan, Senior Technologist and Independent Life Sciences Consultant
3:05 pm

Folding@home Powers Discovery with Next-Gen Data Infrastructure (Innovative Practices Honorable Mention Award)

Gregory R. Bowman, PhD, Associate Professor, Biochemistry & Molecular Biophysics, Washington University
Brian Carpenter, Senior Director, Unstructured Technology, Pure Storage

Folding@home is a distributed computing initiative designed to aid scientists in understanding and treating a wide variety of diseases by simulating protein dynamics. At the start of the pandemic, Folding@home quickly recognized the powerful role it could play in finding ways to combat the SARS-CoV-2 virus. The user community grew exponentially in just weeks – adding more than 400,000 new devices ‒ to make Folding@home the most powerful computer in the world. Finding the right tools to process high volumes of unprocessed data quickly was critical to the organization’s work. Dr. Gregory Bowman, Director of Folding@home, and Pure Storage share how they met this challenge to drive discovery.

3:35 pm

Storage Infrastructure as a Business Strategy

William T Mayo, CIO, Broad Institute

Too often we let technology drive our decisions and forget that all technology should be a manifestation of business strategy. In this talk we will start with our business objectives and explain how each step in our technology evolution was designed toward those goals.  This will not be a technical talk but rather focus on how we have leveraged tools to clear hurdles to achieving our business strategy.

4:05 pm Refreshment Break in the Exhibit Hall with Poster Viewing
4:35 pm

How Research Products Benefit from a Data Infrastructure Platform

Alex Weigel, PhD, Head of Scientific Solution Engineering & Architecture, Roche

Improving productivity of delivering new and better medicines for patients requires new ways to drug discovery. One of the key pillars for doing so is computational biology. This poses a strong demand for data across the value chain. Providing a FAIR, flexible and agile access to data for computation requires to apply new principles for data architecture (i.e., we must leave behind monolithic and inflexible vintage architecture principles we are so familiar with in order to enable a step change in the way we work with data). This talk will focus on and discuss future proof data architecture principles in early research.

Josiah Clark, Chief AI Architect, Liqid Inc.

Modern AI results are driven by massive data movement to and from storage devices and GPU. But traditional system architecture limitations constrain the design possibilities of these solutions. Join Liqid's Chief AI Architect to discuss the AI challenges facing modern research organizations, and a new way to deploy bare metal AI systems via software called Composable Disaggregated Infrastructure (CDI). 

5:35 pm Networking Reception in the Exhibit Hall with Poster Viewing
6:35 pm Close of Day

Wednesday, September 22

7:30 am Registration Open
8:00 am Interactive Discussions (Sponsorship Opportunity) or Morning Coffee

Interactive Discussions are informal, moderated discussions, allowing participants to exchange ideas and experiences and develop future collaborations around a focused topic. Each discussion will be led by a facilitator who keeps the discussion on track and the group engaged. For in-person events, the facilitator will lead from the front of the room while attendees remain seated. For virtual attendees, the format will be in an online networking platform. To get the most out of this format, please come prepared to share examples from your work, be a part of a collective, problem-solving session, and participate in active idea sharing. Please visit the website's Interactive Discussions page for a complete listing of topics and descriptions.

Charles Fan, Founder & CEO, MemVerge

In this discussion, you'll learn: 

  • The challenges of today's extra-exponential growth in data in Genomics research on time-to-discovery, storage, & more.
  • What is Big Memory Computing and how it is helping enterprises like Analytical Biosciences, Penn State University, & TGen reduce time-to-discovery by up to 60%, & power in-memory data services.
  • How analytic pipelines use Big Memory to load terabytes of data in seconds & execute code with zero IO to storage. 
9:00 am Coffee Break in the Exhibit Hall with Poster Viewing

DATA SECURITY AND TRUST ARCHITECTURE

9:45 am Organizer's Remarks

Cindy Crowninshield, Executive Event Director, Bio-IT World Conference & Expo

9:50 am

Chairperson's Remarks

Sanjay Joshi, Global Lead for Healthcare and Life Sciences, Tanium
9:55 am

Data Security and Trust Architecture

Kathleen Moriarty, CTO, Center for Internet Security

The Center for Internet Security, Inc. (CIS) makes the connected world a safer place for people, businesses, and governments. CIS Controls and CIS Benchmarks provide foundational tools to prioritize security program control implementations according to known threats. CIS is the home of the Multi-State Information Sharing and Analysis Center (MS-ISAC), whose mission is to improve the overall cybersecurity posture of the nation's state, local, tribal and territorial governments. All members have access to our Controls, Benchmarks, and software tools to implement them at no-cost. This talk will explain the CIS best practices as well as the resources available.

10:25 am

Talk Title to be Announced

Ketan Paranjape, Vice President, Commercial Business Operations, Roche Diagnostics
10:55 am

A Physician's View of Patient and Data Trust: Use-case Summaries

Dinesh Shah, CEO & Medical Dir, Michigan Physicians Grp

From ER waiting rooms to rural 911 calls to clinical studies with the microbiome to eye-tracking in cardiovascular disease to issues in EMR trust, the nurse-patient and physician-patient trust bonds remain the strongest in the world. Dr. Shah will briefly outline these use-cases along with a "mind-map" approach to trust in EMR systems.

11:25 am

Darkness Falls Fast. Actionable Security Metrics Protect Enterprises

Brian D. Bissett, IT Security Manager, Bureau of Fiscal Service, Department of the Treasury

IT Security is a discipline that has always had too few dollars chasing too many problems. A significant hurdle is when an organization’s security spend is effectively utilized, there are few operational compromises supporting the necessity of the spend. It is important to convey a situational awareness of an organization’s security standing with appropriate metrics when things are operationally satisfactory to prevent enterprise regression to a posture of unacceptable vulnerability. Conventional and novel metrics and algorithms will be discussed with an emphasis on leading prediction focused measurement techniques to advance interventions before they are needed.

11:55 am Session Break and Transition to Luncheon Presentation
12:10 pm Luncheon Presentation (Sponsorship Opportunity Available) or Enjoy Lunch on Your Own
12:55 pm Session Break and Transition to Exhibit Hall
1:10 pm Refreshment Break in the Exhibit Hall with Poster Viewing

PLENARY KEYNOTE PROGRAM

2:10 pm PANEL DISCUSSION:

Trends from the Trenches

Panel Moderator:
Kevin Davies, PhD, Executive Editor, The CRISPR Journal; Founding Editor, Bio-IT World

Since 2010, the “Trends from the Trenches” presentation, given by Chris Dagdigian, has been one of the most popular annual traditions on the Bio-IT Program. The intent of the talk is to deliver a candid (and occasionally blunt) assessment of the best, the worthwhile, and the most overhyped information technologies (IT) for life sciences. The presentation has helped scientists, leadership, and IT professionals understand the basic topics related to computing, storage, data transfer, networks, cloud, data science, and machine learning that are involved in supporting data-intensive science. In 2021, Chris will give the “Trends from the Trenches” presentation in its original “state-of-the-state address” followed by guest speakers giving podium talks on relevant topics. An interactive Q&A moderated discussion with the audience follows. Come prepared with your questions and commentary for this informative and lively session. To stay connected with Trends from the Trenches updates after today and all year, sign up for BioTeam's newsletter here: https://bit.ly/33uO0OY

Panelists:
Chris Dagdigian, Senior Director, BioTeam, Inc.
Fernanda S. Foertter, PhD, Director of Applications, NextSilicon
Karl Gutwin, PhD, Director, Software Engineering Services, BioTeam, Inc.
Adam Kraut, Director Infrastructure & Cloud Architecture, BioTeam, Inc.
3:30 pm Refreshment Break in the Exhibit Hall with Poster Viewing

DATA SECURITY AND TRUST ARCHITECTURE

4:00 pm

PANEL SESSION: Cybersecurity & Trust

Panel Moderator:
Sanjay Joshi, Global Lead for Healthcare and Life Sciences, Tanium

Recent news-cycles have provided ample proof on the importance of cybersecurity and trust. Data currency, accuracy, provenance and trust are on the critical path for digital health, software and manufacturing supply chains, RWD/RWE and the future of clinical trials. Sanjay will host a panel of standards experts and practitioners from the biopharma and healthcare industries.

Panelists:
Brian D. Bissett, IT Security Manager, Bureau of Fiscal Service, Department of the Treasury
Jyotin Gambhir, Founder & Managing Director, SecureFLO LLC
Kathleen Moriarty, CTO, Center for Internet Security
Ketan Paranjape, Vice President, Commercial Business Operations, Roche Diagnostics
Drummond Reed, Chief Trust Officer, Evernym, Inc.
Dinesh Shah, CEO & Medical Dir, Michigan Physicians Grp
Kay Williams, Azure Office of the CTO - Principal Program Manager, Microsoft; Chairwoman, Open Security Software Foundation
5:35 pm Close of Conference





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