Bio IT World Expo 2016  
Bio IT World Expo 2016

Track 3 - April 5 – 7, 2016

Software Applications & Services

Tools that Best Ultilize Data to Drive Scientific Decision Making

Track 3 explores the technology and tools that are used to connect data, applications, people, processes, and partners to ensure available, reliable, and actionable information for scientific decision making. Case studies will be presented that address how life science organizations address common problems in utilizing data including analytics, methods and standards, using open source, semantic technology, using in-house vs. customized commercial platforms, transparency, efficiency, security, and cost-effective solutions.

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Tuesday, April 5

7:00 am Workshop Registration and Morning Coffee

8:00 – 11:30 Recommended Morning Pre-Conference Workshops* Security Considerations for Virtual Research

12:30 – 4:00 pm Recommended Afternoon Pre-Conference Workshops* Growth Strategy: Leveraging Cloud Scalability to Enable Rapid Growth and Change

* Separate registration required

2:00 – 6:00 Main Conference Registration


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5:00 – 7:00 Welcome Reception in the Exhibit Hall with Poster Viewing

Wednesday, April 6

7:00 am Registration Open and Morning Coffee


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9:00 Benjamin Franklin Awards and Laureate Presentation

9:30 Best Practices Awards Program

9:45 Coffee Break in the Exhibit Hall with Poster Viewing


10:50 Chairperson’s Opening Remarks

11:00 Allotrope Foundation: Driving Metadata and Master Data Management through Improved Data Modeling with Semantic Technologies

Dana Vanderwall, Associate Director, Cheminformatics, Research Information Technology & Automation, Bristol-Myers Squibb; Vice Chair, Allotrope Board of Directors

We will briefly describe some of the current data integration and management challenges facing the industry and how the Allotrope Framework provides a semantic basis for improved metadata and master data management through the use of modularized semantic models that capture the most pertinent entities, attributes and relationships needed to capture the plethora of laboratory data.

11:30 An Overview of the RightFind XML for Mining Platform

Haralambos Marmanis, Ph.D., CTO & Vice President, Engineering & Product, Copyright Clearance Center

In the pharmaceutical and biomedical industries, easy access to the complete scientific corpus can become a catalyst for new discoveries in drug and treatment research. We have created a single platform that provides access to full-text XML articles from the most sought after international, peer-reviewed, scientific journals. We will present the current platform capabilities, talk about the problems it solves, and future opportunities.

12:00 pm Integration and Flexibility Supporting Advanced Biologics Processes

Tim Moran, Director, Life Science Research Product Marketing, Dassault Systemes, BIOVIA

The complex processes in Biologics require flexible tools that at the same time support integration and compliance. The Electronic Lab Notebook from BIOVIA, based on an open foundation allows streamlining and integrating the flow of information and tasks within and between teams. It works as an integration hub enhancing efficiency and collaboration while reducing compliance risks for Biologics processes throughout the biotherapeutics lifecycle.

12:15 Sponsored Presentation (Opportunity Available)

12:30 Session Break

12:40 Luncheon Presentation (Sponsorship Opportunity Available) or Lunch on Your Own

1:40 Session Break


1:50 Chairperson’s Remarks

1:55 Enabling Cross-Group Collaboration on Cell Lines via Arxspan’s ArxLab

Bruce Kozuma, Systems Analyst & Project Manager, Broad Information Technology Services, The Broad Institute of MIT and Harvard

Gain insight into how the Broad solved a common and intransigent issue facing a variety of diverse organizations using cloud-based, current generation laboratory data management software in a manner that can be reapplied in a variety of situations. Learn how different departments within the Broad worked collaboratively with Arxspan to solve this issue in a manner horizontally, i.e., differently from either a bottom up or top down approach.

2:25 Regeneron Genetics Center’s Use of the DNAnexus Annex in the Amazon Cloud for Large-Scale NGS Downstream Compute

Christopher Sprangel, Director, IT, Human Genetics, Genome Informatics, Regeneron Genetics Center

The Regeneron Genetics Center (RGC) has worked with DNAnexus to build out a secure but highly flexible high performance compute (HPC) environment in the AWS cloud. This compute environment, providing high scalability and security, is managed by a high-reliability DNAnexus system that provides layered, software-defined compute instances, with continual monitoring and patching of the systems, available in VPCs for general compute use.

2:55 Sponsored Presentation (Opportunity Available)

3:25 Refreshment Break in the Exhibit Hall with Poster Viewing


4:00 Computerized Clinical Decision Support for Laboratory Services: The Brigham and Women’s Hospital Experience

Milenko Tanasijevic, M.D., MBA, Vice Chair for Clinical Pathology, Department of Pathology & Director, Clinical Laboratories, Brigham and Women’s Hospital and Dana Farber Cancer Institute; Associate Professor of Pathology, Harvard Medical School

The talk will focus on our experience with development and deployment of various computerized, physician order-entry driven interventions to improve utilization of laboratory tests. These include lab charge displays, reminders for redundant tests, computerized alerting protocols, messaging about appropriate frequency and timing of therapeutic drug monitoring levels. Their impact on lab utilization will be discussed along with plans for future interventions using our newly implemented EPIC / eCare hospital information system.

4:30 From Bathroom to Healthroom: How Magical Technology Will Revolutionize Health

Juhan Sonin, Director, Design, Mechanical Engineering, GoInvo, MIT

As design harnesses digital, materials and networking technologies, a very new health experience is just over the horizon. Proactive, lifestyle design. Tracking real-time health data. Non-invasive tools. Custom “just for you” treatments based on your actual genome. These are all real technologies, being used by ordinary people. From Bathroom to Healthroom introduces participants to the macro factors shaping these realities, along with an in-depth exploration of the various impacts of and opportunities for design.

5:00 Sponsored Presentation (Opportunity Available)

5:30 – 6:30 Best of Show Awards Reception in the Exhibit Hall with Poster Viewing

Thursday, April 7

7:00 am Registration and Morning Coffee


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10:00 Coffee Break in the Exhibit Hall and Poster Competition Winners Announced


10:30 Chairperson’s Opening Remarks

10:40 Standardized Security Systems: How They Protect Pharmaceutical Data from Breaches

Mollie Shields-Uehling, President, SAFE-BioPharma Association

Information security breaches are a problem. Globalization and digitization of drug development relies on the Web to share information, exposing patient data and scientific intellectual property to hacks. The session reviews standardized security systems, and their use allowing the secure free flow of information across firewalls among collaborating parties. It includes best practices used by stakeholders such as Merck, GSK and Pfizer.

11:00 Possession is 9/10ths of the Law: Considerations and Evaluations for IT Security Policies

Brian Bissett, Senior Member, Baltimore Section, Institute of Electrical and Electronic Engineers (IEEE)

High-level IT security breaches have made the news numerous times over the past year. Despite the awareness of the risks security breaches pose to organizations, they are still occurring with alarming frequency across all enterprises in both the public and private sector. Is this to become the new norm or has it ushered in a catalyst for change?

11:20 Accessing and Utilizing Public Genomic Data: How Hard Can It Be?

Dianne Pacheco, Information Security Officer, The Jackson Laboratory

Gregg TeHennepe, IT Project Manager, The Jackson Laboratory

The world is awash in Big Data, including large public genomic data sets such as TCGA. Access to these data sets is cited as a high-priority need for research programs; however, the technical and administrative logistics can be daunting. In this talk we will cover the security policies and practices needed to satisfy the data use requirements associated with major public genomic data sets.

11:40 Sponsored Presentation (Opportunity Available)

12:10 pm Session Break

12:20 Luncheon Presentation (Sponsorship Opportunity Available) or Lunch on Your Own

1:20 Dessert Refreshment Break in the Exhibit Hall with Poster Viewing


1:55 Chairperson’s Remarks

John M. Conley, J.D., Ph.D., William Rand Kenan, Jr. Professor of Law, University of North Carolina, Chapel Hill; Counsel, Robinson Bradshaw & Hinson

2:00 Featured Presentation: precisionFDA

Taha A. Kass-Hout, M.D., MS, Chief Health Informatics Officer & Director, Office of Health Informatics, FDA

precisionFDA is an informatics cloud-based platform for ensuring the accuracy of Next-Generation Sequencing (NGS) tests by crowdsourcing reference material and data. A key part of President Obama’s Precision Medicine Initiative, it serves as a collaborative research effort that will inform later regulatory pathways and decision making. During this talk, Dr. Taha Kass-Hout, FDA’s Chief Health Informatics Officer, describes the platform and its successes since the December 2015 beta release.

2:30 Featured Presentation: How the Plecosystem, Blockchain, and Federated Data Enclaves will Shape Genomics Innovation and Application: Emerging Initiatives from the Global Alliance for Genomics and Health

John E. Mattison, M.D., Chief Medical Information Officer, Assistant Medical Director, Southern California Medical Group, Kaiser Permanente; Co-Chair, eHealth Workgroup, Global Alliance for Genomics and Health GA4GH

How can we maximize genomic research for the good of all citizens without violating their privacy? We need powerful new approaches to ensure ethical research without unwarranted risk to citizens who consent to use of personal data. The Global Alliance for Genomics and Health includes worldwide institutions seeking consensus on policy frameworks supported by creative technical solutions to achieve these paired goals of higher value and lower risk. I discuss progress to date.

3:00 Featured Presentation: Large-Scale Data Commons for Genomic and Clinical Data and the Changing Landscape for Sharing Research Data

Robert Grossman, Ph.D., Director, Center for Data Intensive Science (CDIS); Core Faculty, Institute for Genomics & Systems Biology and Computation Institute, Professor of Medicine, Section of Genetic Medicine, University of Chicago

Open commons containing large amounts of public biomedical data from the research community can, potentially, dramatically speed up medical research. We describe our experiences developing large-scale open source data commons for genomic and associated clinical data. We also discuss options for integrating and interoperating in-house genomic and clinical data with public data commons and private data partnerships.

3:30 PANEL DISCUSSION: How Will Data Sharing Innovations Fare in the Regulatory Environment?

Moderator: John M. Conley, J.D., Ph.D., William Rand Kenan, Jr. Professor of Law, University of North Carolina, Chapel Hill; Counsel, Robinson Bradshaw & Hinson


Robert Grossman, Ph.D., University of Chicago

Taha A. Kass-Hout, M.D., MS, FDA

John E. Mattison, M.D., Kaiser Permanente

Additional Panelists to be Announced

4:00 Conference Adjourns

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  • Making the World's Knowledge Computable
  • Bioinformatics in the Cloud
  • The Application of Text Analytics to Drug Safety Surveillance

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