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2014 Archived Content

Software Development 

Track 2 explores data handling, workflows, and systems integration activities. Case studies will be presented that address how life science organizations address common problems in the laboratory, business, and clinic – data visualization, managing huge data loads, creating a malleable system that is nimble, speeding-up software development life cycles, and data storage capabilities.

Final Agenda


Download Brochure | Pre-Conference Workshops 


TUESDAY, APRIL 29


7:00 am Workshop Registration and Morning Coffee

8:00 - 11:30 Recommended Morning Pre-Conference Workshops*

Aligning Projects with Organization Strategy

12:30 - 4:00 pm Recommended Afternoon Pre-Conference Workshops*

IT & Informatics in Support of Collaboration and Externalization

*Separate Registration Required. Click here for detailed information.


2:00 - 7:00 pm Main Conference Registration

4:00 Event Chairperson's Opening Remarks

Cindy Crowninshield, RD, LDN, Conference Director, Cambridge Healthtech Institute


4:05 PLENARY KEYNOTE SESSION 

Click here for detailed information.  


5:00 – 7:00 Welcome Reception in the Exhibit Hall with Poster Viewing

 

 


WEDNESDAY, APRIL 30

7:00 am Registration Open and Morning Coffee

8:00 Chairperson's Opening Remarks

Phillips Kuhl, Co-Founder and President, Cambridge Healthtech Institute


8:05 PLENARY KEYNOTE SESSION 

Click here for detailed information.  


9:00 Benjamin Franklin Award & Laureate Presentation

9:30 Best Practices Awards Program

9:45 Coffee Break in the Exhibit Hall with Poster Viewing

10:50 Chairperson's Remarks

Rick Friedman, Specialist, HPC Research Computing & Big Data, Dell


11:00 Featured Presentation:

HPC Trends in the Trenches 2014

Chris Dagdigian, Founding Partner & Director, Technology, BioTeam, Inc.

In one of the most popular presentations of the Expo, Chris delivers a candid assessment of the best, the worthwhile, and the most overhyped information technologies (IT) for life sciences. The presentation time for this talk has been extended from 30 to 60 minutes to accommodate the amount of information that is shared. Plus, Chris won’t feel pressured to speak so fast!


12:00 pm The Pan-Cancer Analysis of Whole Genomes Project

Lincoln Stein, Ph.D., Director, Informatics and Bio-Computing, Ontario Institute of Cancer Research; Professor, Molecular Genetics, University of Toronto

The Pan-Cancer Analyis of Whole Genomes project aims to understand common and distinguishing patterns of variation among a diverse set of cancer types. We are performing uniform computational processing of the whole genome sequencing data from the tumors and normal control DNA of more than 2000 donors in order to eliminate differences that are due to different ways of analyzing the data.  


 

Arista12:40 Luncheon Presentation I: Cloud Networking Agility Drives Biotech Innovation & Discovery 

Chris Campbell, Data Center Specialist, Arista Networks, Inc.

BigData-methods for BioTech now require new hybrid-use of map/reduce & SQL techniques to achieve ever more meaningful correlations across more varied forms of data and across more locations where data resides. Arista and best-of-breed technology partners deliver one simple, leaf-spine, open-standard network topology to span and to scale, to support all applications across all the datastores that scientists wish to combine. Driven by automation-enabled Software-Defined Cloud Networking, Arista applies cloud-like agility and scale for lowest OPEX and unprecedented innovation potential. 

 

 

IBM1:10 Luncheon Presentation II: IBM’s Comprehensive Reference Architecture for Genomic Medicine 

Frank Lee, Ph.D., Senior Certified Solution Architect, Technical Advisor, Life Sciences, IBM Technical & Platform Computing Worldwide

Dr. Frank N. Lee will describe IBM’s open and extensible reference architecture for genomic medicine, including integration of genomic data within a translational platform. The architecture describes a unique, converged platform for high-throughput genomics and analytics through on-premise, cloud and hybrid delivery. It includes a scalable data repository, powerful workload engine and genomics application center for commonly used applications. 

Harnessing Data & Standards 

1:50 Chairperson's Remarks

John A. Norris, J.D., MBA, Chairman, Norris Capital, Inc. and FDDH, Inc.; Senior US Advisor to Kanagawa, Japan, Governor Kuroiwa and GCC

1:55 HELM: An Open Standard for the Representation of Complex Biomolecules

Sergio Rotstein, Ph.D., Director, Research Business Technology, Pfizer, Inc.

The steady increase in therapeutic research involving complex biologic entities has exposed a gap in the ability of traditional informatics tools to deal gracefully with these types of molecules. HELM is a new open standard that enables the representation of a diverse set of complex macromolecules such as oligonucleotides, proteins, antibodies, antibody-drug conjugates, etc., including those containing unnatural and chemically-modified components. This presentation will describe the HELM standard and associated toolkit, its origins and use at Pfizer, and the Pistoia Alliance HELM project that has transitioned the technology into the open source, making it available freely and openly to the biopharmaceutical industry at large.

2:15 Looking at Clouds from Both Sides Now: Systems, Dataflow and the Future of Drug Development

Greg Koski. M.D., Ph.D., President and Co-Founder, Executive Office, Alliance for Clinical Research Excellence and Safety

2:35 Summary: FDA Software-Tools Reform  

John A. Norris, J.D., MBA, Chairman, Norris Capital, Inc. and FDDH, Inc.; Senior US Advisor to Kanagawa, Japan, Governor Kuroiwa and GCC  
This presentation discusses the efforts of the Global Collaborative Center (GCC) in helping to reform the U.S. FDA’S review methods and standards relating to data/business intelligence analytics and decision-support software tools for new medical device products. To view longer abstract, please click here.

2:55 Metabolync™: A Cloud-Based Solution for Sharing, Visualizing and Analyzing Metabolomics Data
Corey DeHaven, Vice President, Information Systems, Metabolon, Inc. 

Metabolomics experiments may generate a large amount of data including both named and unnamed metabolites, group statistical analysis and biological pathway annotations. Data visualization and analytical tools are required to aid in understanding the data and relationships among detected metabolites and their effects on the underlying biology. Metabolync™ leverages cloud-based resources and web service API's to enable these functions.

3:10 Accelerate Insights – Processing Intense Simulations and Big Data Analysis
Nick Ihli, Senior Systems Engineer, Adaptive Computing 
Adaptive powers the world’s largest and most robust datacenters with its scheduling and optimization software, Moab. Moab plays a huge role in accelerating insights for researchers and IT professionals. Learn about how Big Workflow accelerates insights by efficiently procession intensesimulation and big data analysis- unifyingHPC, cloud and datacenterresources, optimizing the analysis process and guaranteeing services to the business -speeding time to discovery.  

3:25 Refreshment Break in the Exhibit Hall with Poster Viewing


Data Integration and Business Intelligence 

4:00 Transforming Scientific Information into Business Intelligence through Search-Based Applications

Robert Hernandez, Informatics Scientist, AstraZeneca

The inability to harness data for scientific decision-making is a problem that negatively impacts organizations worldwide. The AstraZeneca R&D search vision is to leverage internal and external data and create insights that deliver novel search-based business applications. This presentation demonstrates the power of building search-based applications that leverage 200 million scientific documents as a solution.

4:30 In Pursuit of Knowledge Management: The Implementation of a Highly Adopted Database within a Drug Substance Process Development Department

Russell Van Buskirk, Senior Associate Scientist, Purification Process Development, Amgen

As development timelines decrease, knowledge management of drug substance development data becomes essential. Historically, the adoption of searchable databases requiring dedicated data entry by scientific staff has been low. The time savings inherent in electronic lab notebook templates with automatic report generation capabilities is perceived by the scientific staff as a benefit to their daily work flow and increases adoption with the added benefit that the template doubles as a future searchable database.

5:00 Utilizing Amazon Web Services for Data Collection, Integration, and Analysis in the Life Sciences

Angel Pizarro, Solutions Architect, Amazon Web Services

Life science organizations of all sizes, from big pharma to academic and government research institutions, have achieved success using Amazon Web Services cloud computing to architect and run infrastructure for data ingestion, integration, analysis, and collaboration. AWS provides a comprehensive portfolio of web services that can be combined for creating cost-effective solutions for life science data workloads. In this talk, we will showcase AWS big data services such as Amazon Kinesis, Amazon Elastic Map Reduce, and Amazon Redshift to describe how you can get real-time streaming, analytics, and data warehousing to support business intelligence solutions in minutes.

5:30 - 6:30 Best of Show Awards Reception in the Exhibit Hall


THURSDAY, MAY 1

7:00 am Registration Open

7:00 Breakfast Presentation (Sponsorship Opportunity Available) or Morning Coffee

8:00 Chairperson’s Opening Remarks

Kevin Davies, Ph.D., Vice President Business Development & Publisher C&EN, American Chemical Society; Founding Editor, Bio-IT World


8:05 PLENARY KEYNOTE SESSION 

Click here for detailed information.  


10:00 Coffee Break in the Exhibit Hall and Poster Competition Winners Announced


Integrating and Implementing Analysis Platforms and Data Workflows 

10:30 Chairperson's Opening Remarks
Brian Bissett, IT Specialist, Office of Systems, Social Security Administration 

10:35 From Animal to Image - Integrating a Research Pathology Lab Environment at Roche pRED

Angelika Fuchs, Ph.D., Senior Scientist, pRED Informatics, Roche pRED

We present an exemplary case study where several components (in house implemented tools as well as customized commercial platforms) have been successfully integrated into a departmental system landscape for the pathology department in Roche pRED leading to a strong increase in transparency as well as efficiency. One major component is the first installation of a system for sample tracking used in routine pathology labs within a pharma research environment exemplifying how innovation originating from the clinical and diagnostic space can be used with great benefit within a pharma exploratory research environment.

10:55 Navigator Workbench - An Integrated Analysis Platform for Modeling & Simulation

Alexandra Grebe de Barron, Ph.D., Consultant, R&D IT Early Development, Bayer Pharma AG

We will present an integrated platform for modeling and simulation (population PK/PD analysis) in a regulated environment. The first results of the proof-of-concept at Bayer Pharma AG will be shown. The solution includes an internal high-performance cluster for routine analysis and a private external cloud for peak computing demands. Data security and validation approach will also be presented.

11:15 Enterprise Level SharePoint Administration for Program Management

Brian Bissett, IT Specialist, Office of Systems, Social Security Administration

SharePoint is rapidly becoming ubiquitous as the tool of choice for online collaboration, document management, portals, workflows, approval chains, and intranet sites. Using InfoPath, SharePoint’s capabilities can be expanded to design, distribute, file, and submit electronic forms containing structured XML data. Numerous third party tools can expand both SharePoint and InfoPath’s capabilities far beyond their original scope to include functions such as Project Management, Dashboarding, and Asset Management. Limitations, pros and cons, and cost effective solutions will be discussed.

11:35 Implementation and Deployment of a Workflow Management System for AbbVie’s Antibody Engineering Groups
Ankita Bhan, PMP, Scientist Informatics, Scientific Informatics and Automation, AbbVie 

In order to address the existing and anticipated needs of Antibody engineering groups across the sites at Abbvie, we need to deploy technology based platforms covering the next gen biologics research. Here, we will focus on the successful management of an implementation and deployment project for Abbvie’s antibody lead discovery group leveraging the solution offered by Genedata Biologics.

Thomson Reuters-Large12:15 pm Luncheon Presentation I: BI-SMART - A Work-Flow Based tranSMART System Enabling Scientists for Fast and Reliable Genomic Analysis
Will Loging, Director, Computational Biology, Boehringer Ingelheim  

12:45 Session Break

1:15 Dessert Refreshment Break in the Exhibit Hall with Poster Viewing


Managing Big Data and Security Strategies 

1:55 Chairperson's Remarks

Toby Bloom, Ph.D., Deputy Scientific Director, Informatics, New York Genome Center

2:00 Data and Intellectual Property Security in a Global Cyber Environment

Russ Brown, Supervisory Special Agent, Boston Division Criminal Cyber Squad, FBI

Data security is a very significant issue faced by businesses in today’s electronically connected environment. Data “owned” or controlled by a business, as well as applications developed by a business, are categorized as Intellectual Property. The security and protection of Intellectual Property is critical to conducting, maintaining and growing a secure business in the current global environment.

PodcastLogo

2:30 Information Classification: The Key to a Sane Security Strategy

William Telford, Director, R&D IS Security, Sanofi R&D

Understanding your information is key to your security success and enables collaboration. This talk will address the key topics to consider and challenges that must be overcome.

3:00 PANEL DISCUSSION: The Big Data Storage and Security Maze: Balancing Collaboration and Privacy

Moderator: Toby Bloom, Ph.D., Deputy Scientific Director, Informatics, New York Genome Center

Russ Brown, Supervisory Special Agent, Boston Division Criminal Cyber Squad, FBI

Yaniv Erlich, Ph.D., Principal Investigator and Whitehead Fellow, Whitehead Institute for Biomedical Research

Philip Groth, Ph.D., IT Business Partner, CoE Research, Bayer HealthCare Pharmaceuticals

John Sabey, President, Sabey Data Center Properties

William Telford, Director, R&D IS Security, Sanofi R&D

Big data has led to organizations turning to virtual networks for information storage and processing. Thus, unauthorized access to data and implementation of effective governance structures are growing concerns. To balance knowledge sharing and respect for confidentiality, researchers must consider how and where to store and secure data – plus what data and why. This panel gathers representatives from academia, pharma and IT to discuss these issues. Topics include:

  • How secure is your data?
  • When should you favor data sharing and when should you restrict data flow?
  • What data actually needs to be protected in the first place?
  • What security systems and practices are most appropriate for specific research needs?

4:00 Conference Adjourns

*IBM and the IBM logo are trademarks of International Business Machines Corp., registered in many jurisdictions worldwide.  



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  • Making the World's Knowledge Computable
  • Bioinformatics in the Cloud
  • The Application of Text Analytics to Drug Safety Surveillance
 

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