TUESDAY, APRIL 24
7:00 am Workshop Registration and Morning Coffee
8:00 am - 4:00 pm Pre-Conference Workshops*
- Beyond the Cloud: Improving the R&D Innovation Process through Cloud Services
- Cloud Computing
*Separate Registration Required
2:00 - 7:00 pm Main Conference Registration
4:00 Event Chairperson's Opening Remarks
Cindy Crowninshield, RD, LDN, Conference Director, Cambridge Healthtech Institute
4:05 Keynote Introduction
Sanjay Joshi, Solutions Architect, Life Sciences, EMC Isilon Storage Division
4:15 PLENARY KEYNOTES
Martin Leach, Ph.D., CIO, Broad Institute of MIT and Harvard
Jill P. Mesirov, Ph.D., Associate Director and Chief Informatics Officer; Director, Computational Biology and Bioinformatics, Broad Institute of MIT and Harvard
5:00 - 7:00 Welcome Reception in the Exhibit Hall with Poster Viewing
Drop off a business card at the CHI Sales booth for a chance to win 1 of 2 iPod touches® or 1 of 2 Xbox 360s®*!
*Apple® is not a sponsor or participant in this program
Wednesday, April 25
7:00 am Registration and Morning Coffee
7:55 Chairperson's Opening Remarks
Phillips Kuhl, Co-Founder and President, Cambridge Healthtech Institute
8:00 Keynote Introduction
Bas Burger, President, Global Commerce, BT Global Services
8:15 PLENARY KEYNOTE
Eric D. Perakslis, Ph.D., CIO and Chief Scientist of Informatics, U.S. Food and Drug Administration
8:45 Benjamin Franklin Award & Laureate Presentation
9:10 Best Practices Award Program
9:45 Coffee Break in the Exhibit Hall with Poster Viewing
10:50 Chairperson's Remarks
Christopher Brown, CTO, Opscode
11:00 Building a Scalable Pharmacometrics Platform in the Cloud
Jeffrey Hane, Ph.D., COO and CIO, Metrum Research Group
Adam Kraut, Senior Scientific Consultant, Services, BioTeam
Moving single applications to the cloud is yesterday's news. Today we build agile infrastructures for leading edge research providers. From elastic HPC clusters to collaborative decision support systems, we will reveal the challenges and introduce best practices in modern research computing in the cloud.
11:30 CVRG: Making Cardiovascular Collaborations Easier in the Cloud
Stephen Granite, Director of Database and Software Development, Center for Cardiovascular Bioinformatics and Modeling, Institute for Computational Medicine, The Johns Hopkins University
The cardiovascular (CV) community needs software tools for managing diverse types of CV data. These tools must be secure, well-documented and easy to use. The CV Research Grid (CVRG) serves the needs of basic and clinical researchers by providing seamless, secure access to study datasets and analysis tools. A lesson learned early on was that the vast majority of CV studies lack IT support, and therefore study sites are not able to install and operate complex software applications on their own. The CVRG has therefore moved towards the Software as a Service approach, delivering powerful data management and analysis tools to our users that are accessed through the web browser.
12:00 pm HVC -High Volume Computing - Going Where No Research Has Gone Before
Jason Stowe, CEO Cycle Computing
There was a time when it wouldn't even have been considered - too few computing resources, too much time to complete. But now taking a 10, 20, 100 or 1000 year compute problem and solving it by deploying a very large scale (10s of thousands of cores) compute cluster in the cloud is real. Cycle Computing has taken cloud HPC to new heights of scale and agility. The unthinkable research is now doable. Securely.
12:30 Luncheon Presentation
Federation of the Cloud – A World of OptionsMichael Cardy, M.Sc., Global Chief Technology Officer, OnX Enterprise SolutionsThe Cloud continues to rapidly evolve — the latest phase being the Federated Cloud. As organizations look to leverage existing investments in cloud infrastructure residing in their data centers and seamlessly integrate with an external provider's cloud, they realize both elements must work together in federation. Join OnX Enterprise Solutions as we explore the impact and opportunities of federated cloud services.
1:40 Chairperson's Remarks
Peter J. Boler, Vice President, Life Sciences & Healthcare, Persistent Systems
1:45 Hybrid Strategies for Biomedical Research Data Management
Vas Vasiliadis, Director, Products, Computation Institute, University of Chicago
While some early adopters have realized benefits by incorporating clouds into their analysis pipelines, many challenges remain. In this presentation we will highlight the critical issues associated with research data management, and describe alternative approaches for addressing these challenges by optimizing the use of local, distributed and cloud-hosted resources.
2:15 Building a Collaborative Informatics Platform for Translational Research: An IMI Project Experience
Yike Guo, Ph.D., Professor, Computing Science, Computing, Imperial College London
In this presentation, we present the design and development of a collaborative research platform for cross-institutional collaborative clinical/ preclinical research and biomarker discovery. Such a platform contains a rich set of advanced methods and systems for large-scale omics data analysis and supports KM tasks for European IMI projects in large scale.
2:45 Next Generation Bioinformatical Analysis on the Cloud
Sifei He, Director, BGI Cloud, BGI; Xing Xu, Senior Product Manager, Bioinformatics Center, BGI; Lin Fang, Director, Bioinformatics Center, BGI
While the $1000 genome continues to be a thrilling race, effective genome data mining, interpretation and management presents substantial scientific and technology challenges. This session will share BGI's vision and strategy followed by a LIVE DEMO on BGI Cloud, a key enabling platform that provides efficient and undisruptive way to consume streamlined bioinformatical analysis services for future genomics research and monetization.
3:15 Refreshment Break in the Exhibit Hall with Poster Viewing
3:45 Balancing and Augmenting Local Resources with Remote Clouds
Angel Pizarro, Director, ITMAT Bioinformatics Facility, Institute for Translational Medicine and Therapeutics, University of Pennsylvania
Data production advances in next-generation sequencing caused a shortage of compute and data center resources for the Penn Genome Frontiers Institute. Local resources could not be procured fast enough to meet demand. PGFI turned to The Cloud to expand its computational capacity. This talk will consist of a deep-dive technical discussion about enabling technologies that were used to augment local high-performance compute clusters with external cloud resources.
4:15 Virtual Screening On Demand in the Amazon Cloud
Donovan Chin, Ph.D., Senior Investigator I, Novartis Institute for Biomedical Reseach
Virtual Screening is a tool for drug discovery that uses computational power and computer models of drug interaction to filter very large collections of chemical compounds down to a manageable number that may tested for bioactivity. We will discuss our efforts to expand this tool onto the Amazon cloud in way that is able to meet the immediate needs of drug discovery, while at the same time leveraging our internal cloud computing environment in an efficient and cost effective way.
4:45 HP Sequence Services - Building an Open Commercial NGS Platform
Etzard Stolte, Ph.D., CTO, Life Sciences, Hewlett-Packard EMEAOffering a secure, easy-to-use, pay-as-you-go Cloud service for next-generation-sequence analysis and storage is challenging. With real-world requirements like proper application life-cycle-management, regional data constraints, and analysis quality control, building an open commercial NGS platform becomes a hard IT problem. This presentation will introduce key successes and compromises made during implementation of HP Sequence Services.
5:15 Best of Show Awards Reception in the Exhibit Hall
6:15 Exhibit Hall Closes
THURSDAY, APRIL 26
8:00 am Featured Speaker Introduction
David A. Medina, Director, Product Management, Healthcare Analytics & Life Sciences, Business Solutions, Hewlett-Packard
8:10 Featured Speaker: HPC Trends from the Trenches
Chris Dagdigian, Founding Partner and Director of Technology, BioTeam, Inc.
HPC Trends from the Trenches is one of the most popular presentations of the Expo! This talk will present how common HPC problems in life science informatics have been approached by organizations of varying type and size. We will discuss observed trends in computing, workflows and data movement, along with details on particularly clever solutions observed in production environments around the world.
8:40 Chairperson's Opening Remarks
Michael A. Schulman, M.Sc., Director, Marketing, ScaleMP, Inc.
8:45 Enabling Research in the CloudMatt Wood, Ph.D., Product Manager for HPC and Big Data, Amazon Web Services
Panel Discussion: HPC/Life Science in the CloudModerator: Deepak Singh, Ph.D., Principal Product Manager, Amazon EC2, Amazon Web ServicesPanelists:
Anushka Brownley, Product Manager, Cloud Project, Complete Genomics
Angel Pizarro, Director, Institute for Translational Medicine & Therapeutics, University of Pennsylvania
Stephen Litster, Ph.D., Global Lead, Scientific Computing, Novartis Institute for Biomedical Research
9:45 Beyond the Cloud: How Cloud Services Can Drive Performance in Pharma R&D
John Gillam, IT Services Programme Director, BT Global Services
As so much of the debate about cloud computing has focused on technology, this presentation will look at why pharma should focus on the benefits of cloud services and how it can drive performance in R&D. We will discuss what organizations need to do to make cloud solutions work for them along with the how and why.
10:15 Coffee Break in the Exhibit Hall and Poster Competition
10:45 Plenary Keynote Panel Chairperson's Remarks
Kevin Davies, Ph.D., Editor-in-Chief, Bio-IT World
10:50 Plenary Keynote Panel Introduction
Geoffrey Noer, Senior Director, Product Marketing, Panasas
11:00 Plenary Keynote Panel:
A special plenary session featuring trends and challenges in cancer research:
Julian Adams, Ph.D., President, Research and Development, Infinity Pharmaceuticals, Inc.
Jose Baselga, M.D., Ph.D., Chief and Bruce A. Chabner Chair, Division of Hematology/Oncology, Massachusetts General Hospital; Associate Director, Massachusetts General Hospital Cancer Center; Professor of Medicine, Harvard Medical School
Sir John Burn, MD, FMedSci, Professor of Clinical Genetics, Institute of Genetic Medicine, Newcastle University, UK; Genetics Lead, National Institute of Health Research, UK; Medical Director, QuantuMDx Ltd
John Quackenbush, Ph.D., Professor, Biostatistics and Computational Biology, Cancer Biology Center for Cancer Computational Biology, Dana-Farber Cancer Institute
12:15 Luncheon in the Exhibit Hall with Poster Viewing
1:55 Chairperson's Remarks
Rich Furr, Head, Global Regulatory Affairs and Chief Compliance Officer, Staff, SAFE-BioPharma Association
2:00 An Expert's Guide through the Identity Landscape
Rich Furr, Head, Global Regulatory Affairs and Chief Compliance Officer, Staff, SAFE-BioPharma Association
The presentation will provide an overview of US and EU government and industry-driven identity management initiatives to develop a trusted internet identity capability community. It will cover topics like identity credentials, identity trust infrastructures, applicable standards, governance models and approaches to cloud based identity management.
2:30 Solution-as-a-Service: Pharmacovigilance Systems on the Multi-Tenanted Platform
Ramin Daron, IT Director, Information Technology, Johnson & Johnson
This presentation is intended to engage industry in discussion about the viability and the challenges to be cleared in order for the multi-tenanted PV Platform to be operationalized at scale and to acheive its value proposition. Concepts of data ownership and security, performance metrics, architectural decisions and changing perceptions to be offered for consideration.
3:00 Clinical Trial Simulations Using Cloud Computing
Russell Towell, Senior Informatics Engineer, Scientific Computing Services, Bristol-Myers Squibb
Tarek Leil, Director, Cardiovascular and Metabolics Pharmacometrics, Bristol-Myers Squibb
Clinical trial simulations are an integral part of the drug development process and require CPU intensive compute resources. Leveraging cloud computing to provision CPU clusters can dramatically reduce the cycle time of trial simulations enhancing its application across drug development portfolios.
3:30 Closing Featured Speaker IntroductionJonathan Sheldon, Ph.D., Global Senior Director, Translational Medicine, Oracle Health Sciences
3:40 Closing Featured Speaker:
GeneStack — Universal Platform for Genomics Application Development
Misha Kapushesky, CEO GeneStack Ltd.
4:00 Conference Adjourns
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