Track 1 will delve into high performance computing and computing platforms, including grid computing, datacenter design and data storage (storing solutions, data security, standards & regulations, access issues, system interoperability).

TUESDAY, APRIL 20

2:00 - 6:00 pm Main Conference Registration

4:00 Event Chairperson’s Opening Remarks

Cindy Crowninshield, Conference Director, Cambridge Healthtech Institute

Sponsored by
  4:05  Keynote Introduction: Ronald Ranauro, Chief Executive Officer, GenomeQuest, Inc. 

4:15 PLENARY KEYNOTE: Drug Discovery Opportunities and Challenges -- VC, Biotech and Pharma Perspectives Christoph Westphal, M.D., Ph.D., CEO, Sitris Pharmaceuticals; Senior Vice President, Center of Excellence for External Drug Discovery, GlaxoSmithKline

 

5:00 - 7:00 pm Welcome Reception in the Exhibit Hall

***Drop off your business card at the CHI Sales Booth for a chance to win an Apple® - iPod nano®! 2 Winners will be announced at 6:45pm in the Exhibit Hall

 

WEDNESDAY, APRIL 21

 

7:30 am Registration and Morning Coffee

8:15 Event Chairperson’s Opening Remarks

Phillips Kuhl, Co-founder and President, Cambridge Healthtech Institute

Sponsored by
 Keynote Introduction: Jamie Wyatt, Vice President and General Manager Health and Life Sciences, Netezza

8:20 PLENARY KEYNOTE: Impact of HIT Stimulus on Novel Sources of Data for Research John Halamka, M.D., M.S., CIO, Harvard Medical School           9:00 Keynote Presentation & 2010 Benjamin Franklin Award  Alex Bateman, Ph.D., Senior Investigator, Pfam Database Project, Wellcome Trust Sanger Institute

 

Sponsored by
 9:30 Coffee Break, Poster and Exhibit Viewing
***Drop off your business card at the CHI Sales Booth for a chance to win 1 of 2 Prizes! (Nintendo® Wii™ System or Apple® - iPod touch®)

 

Scaling Up For The Data Deluge

10:50 Track Chairperson’s Remarks “HPC from the Trenches”

Chris Dagdigian, Founding Partner and Director of Technology, BioTeam, Inc.

11:00 Sanger Centre’s Perspective on Data Storage Challenges

Phil Butcher, Head of Systems, Sanger Centre

As the largest sequencing centre in Europe, the Sanger Institute makes a massive contribution to the worldwide collection of genomic information. A key challenge is identifying an appropriate storage infrastructure to manage the onslaught of raw data that continues to be generated. This talk will present Sanger Institute’s perspective on scaling techniques and practical issues they are considering that address the data storage challenge.

11:30 Adjusting to the New Scale of Research Data Management

Matthew Trunnell, Acting Director, Advanced IT, Broad Institute of MIT and Harvard

One of the Broad Institute’s core missions is to discover, develop and optimize the critical technologies needed to obtain and analyze the massive amounts of genomic data being generated by scientists at the Broad and around the world. Much of our attention in recent years has been focused on scaling our IT infrastructure to accommodate the influx of data resulting from second-generation sequencing and other high-throughput technologies, but it is only recently that we have started to come to terms with some of the secondary impacts of the data scale-out. In this talk I will discuss how the Broad been exploring new approaches to the challenges of data protection and long-term data management at our current multi-petabyte scale with particular emphasis on the increased responsibility of researchers in the data management process.

12:00 pm Maximizing Research and Minimizing Storage Expenditure: Analyzing a Production Deployment of Deduplication & Compression for Bioinformatics
Carter George, Vice President of Products, Ocarina Networks
In all Bioinformatics disciplines, rich data is the platform from which all discovery is made, and rapid throughput growth of highly anticipated next-generation scanning systems means faster time-to-discovery. However, with each increase in scanner throughput comes a corresponding requirement for additional storage. Because scanner throughput is out-pacing disk system density, bioinformatics organizations may be allocating more and more of their budgets to IT and less to research. The deployment of cheaper disk is attractive, but imposes higher administrative costs.
This presentation will review various solutions to keeping IT expenditures in check, without sacrificing on enterprise-class reliability and scalability features. Much of the presentation will be devoted to reviewing the process of selection, deployment, and results of a major bioinformatics institution's deployment of deduplication and compression to improve utilization of existing storage and reduce costs.

 

Sponsored by
12:30 Luncheon Presentation

Enabling World Class Research through Innovative Data Management Strategies
Peter Brey, WW Business Development Manager, Scalable NAS, HP Storage
Brent Richter, Director, Enterprise IS, Partners HealthCare Systems
In the past five years, Partners HealthCare Center for Personalized Genetic Medicine focused its efforts on building an IT foundation with the right hardware and software to support their vision of personalized medicine, where clinicians are able to make treatment and medication decisions based on patient's genetic profile.
For organizations like Partners HealthCare Center for Personalized Genetic Medicine there is an on-going concern that IT must keep pace with the biology, especially in terms of storage capabilities.  As the costs of sequencing technologies continue to fall and the volumes of data from those technologies continue to rise, that concern becomes a reality that IT must graple with daily. 
IT continues to play a significant role in supporting the vision of personalized medicine, implementing a scalable storage solution is an important component in realizing the benefits of next generation sequencing technologies.

1:40 Track Chairperson’s Remarks

David Medina, Worldwide Life Science and Pharma Segment Executive, Hewlett Packard

 

1:45 IT Infrastructure Strategy in Support of Next-Gen Biological Research

Gregg TeHennepe, Senior Manager, Research Liaison, Information Technology, The Jackson Laboratory

The Jackson Laboratory is a leading genetics laboratory. This talk presents our 2009 Research Information Technology Whitepaper documenting The Jackson Laboratory’s five-year IT infrastructure plan. Attendees will learn about the methods behind the whitepaper and understand the key research drivers. This talk will review the current status of Jackson’s IT infrastructure supporting research today, how the institution compares to its peers, and provide recommendations for meeting the five year needs of its research programs.

2:15 Improving Storage Efficiency for Unstructured Research Data

Richard Shaginaw, Project Manager, Scientific Computing Services, Bristol Meyers Squibb

This presentation offers insight into an infrastructure approach that expedites growth and change in the research environment while containing costs. The fire hose of data from discovery-related sources requires rapid storage provisioning, manageable yet flexible access controls, and reliable data protection. Supplying these needs by way of a central file service -- large networks of applications using a common file server -- allows us to be more responsive to research requirements, to protect data more effectively, and to reduce management overhead. The novelty of this approach lies in removing the need to manage disk and freeing us to work with the researcher to address data challenges. The audience will learn that for many research purposes, central file-based storage with unified access control is empowering and more efficient than older approaches.

Sponsored by
2:45 Teradata's Agile Analytic Cloud for Research & Development

Joy King, Senior Pharmaceutical Industry Consultant, Teradata

Teradata's Private Agile Analytic Cloud solution and its new "Elastic Mart" functionality allows end-users (scientists, statisticians, data analysts) to integrate data that may reside on public web sites, or their own desktop, with data that resides in the data warehouse -- with no IT intervention. The solution supports agile, iterative analyses using commonly available statistical and visualization tools. Results can easily be published to the data warehouse when ready since all work takes place inside the private cloud and takes full advantage of the power and performance of the Teradata MPP Data Warehouse Platform. Elastic Marts can also easily be monitored and managed by IT via a web tool that is part of the solution. Teradata clients are generating results faster and at a higher capacity. They are able to share and reuse data and results in near real-time. Our customers are realizing business value on day one after they implement our Agile Analytic Cloud solution!

Sponsored by
3:00 IBM Research Solutions for Life Sciences      
Michael Hehenberger, Ph.D., Life Sciences Business Development Executive, IBM Thomas J. Watson Research Center

 

3:15 Refreshment Break, Poster and Exhibit Viewing
***Drop off your business card at the CHI Sales Booth for a chance to win 1 of 2 Prizes! (Nintendo® Wii™ System or Apple® - iPod touch®) Winners will be announced at 3:30pm in the Exhibit Hall

 

3:45 ResearchStation: A Bioinformatics Platform for Research Collaboration in Translational Medicine

Lynn H. Vogel, Ph.D., FHIMSS, FCHIME, Vice President and CIO, Associate Professor, Bioinformatics and Computational Biology, The University of Texas M. D. Anderson Cancer Center

M.D. Anderson’s IT division developed a unique SOA-based IT platform to easily access, integrate and analyze genomic and clinical data. This application, called ResearchStation, enables collaboration between life science researchers utilizing disparate data sources and the analytic tools of their choice, and demonstrates the effectiveness of a SOA-based architecture in enabling interoperability in support of translational research. Learn how life science research organizations are dealing with the challenges of data explosion, how industry partnerships are essential to increase probability of successful outcomes for patients, and how IT continues to contribute to the understanding of translational medicine.

4:15 Building a Translational Biomarker Data Mining Platform:
What Does it Take?

Daniel Ingber, Senior Manager, Information Systems, MedImmune

Biomarker Data Mining (BDM) will lead to a better understanding of drug action, an improved ability to understand physiological responses, and better overview of interrelationships between research and clinical data. MedImmune just completed building a BDM platform to extract, transform, and load (ETL) data from various disparate storage locations and formats such as current databases and spreadsheets, and assemble and present correlated data for exploratory analyses. This talk presents how this flexible data model supports a scalable, industrial-strength scientific data pipeline.

Sponsored by
4:45 Breaking Through the Real World Data Storage Barriers
Björn Andersson, Director of Product Marketing, BlueArc Corporation
Shared storage environments in the real world need broad and robust performance that can deliver through crunch times and scale as necessary when the characteristics of the application workload change over time. Flexibility, open architectures and the tools to support smart data migration and efficient operation are key for a well functioning system. Knowing your application characteristics is more important than relying on narrow benchmark numbers
The session will cover:
- How the unique BlueArc architecture provides the foundation needed for real world data intensive applications
- How smart tools enable you to migrate your data to storage technologies optimized for your applications
- Experience from application level testing with real world data sets
 

5:15 – 6:15 2010 Best of Show Awards in the Exhibit Hall

6:15 Exhibit Hall Closes

Sponsored by
6:30 – 10:00 2010 Best Practices Awards Reception & Dinner

 

 

 

 

 

THURSDAY, APRIL 22

8:00 am Registration and Morning Coffee

Sponsored by
8:45 Event Chairperson’s Opening Remarks

Kevin Davies, Ph.D., Editor-in-Chief, Bio-IT World
Keynote Introduction:  Eric Blatte, Vice President of Sales, Commercial & Public Sector, Imprivata

8:50 PLENARY KEYNOTE: There is No Magic, There is Only Awesome: Scientific Computing with Amazon Web Services Deepak Singh, Ph.D., Business Development Manager, Amazon Web Services   Presentation delivered via a live, interactive videoconferencing platform.       9:30 KEYNOTE PANEL The Future of Personal Genomics A special plenary panel discussion featuring: James Heywood, Co-founder and Chairman, PatientsLikeMe Dan Vorhaus, J.D., M.A., Attorney, Robinson, Bradshaw & Hinson; Editor, Genomics Law Report Dietrich Stephan, Ph.D., President & CEO, Ignite Institute Kári Stefánsson, MD, Dr Med, Executive Chairman and President of Research, deCODE genetics Kevin Davies, Ph.D., Editor-in-Chief, Bio-IT World

 

10:30 Coffee Break, Poster Competition, Vendor Theater Presentations and Exhibit Viewing
***Drop off your business card at the CHI Sales Booth for a chance to win 1 of 2 Prizes! (Nintendo® Wii™ System or Apple® - iPod touch®)

 

SEQUENCING, GENETICS DATA
MANAGEMENT GRID COMPUTING

10:55 Track Chairperson’s Remarks  
Bob Schoettle, Chief Marketing Officer, Panasas, Inc.

11:00 Pallas, a Computational Analysis Network

Daniel McGoldrick, Ph.D., Associate Bioinformatics Scientist, Information Sciences, St. Jude Children’s Research Hospital

The focus of this talk will center on the development and implementation of a computational analysis network (Pallas) at St. Jude Children’s Research Hospital. This system is being developed to facilitate data collection, correlation, and computation using a virtualized storage system and standards based pipeline and workflow architecture. The primary driver of this project is a proposed ‘Pediatric Genome Project’, in which 120 complete genomes will be sequenced using high throughput next-gen technologies. This, along with the validation studies will produce an estimated two to four pedabytes of data and tens of thousands of human interactions with this data. Attendees will understand the approach used to integrate research data and workflows across the many disciplines.

11:30 The Use of Grid Computing to Drive Data-Intensive Genetic Research

Jorge Andrade, Ph.D., Research Scientist, Bioinformatics, Lilly Singapore Center for Drug Discovery

This talk discusses the implementation of a grid computing approach that executes thousands of genotype simulations in parallel, tremendously reducing computational time. A high-resolution genetic study will be used as a case example.

Sponsored by
12:00 pm Enabling World Class Research through Innovative Data Management Strategies
Patrick Osborne, WW Business Development Manager, Scalable NAS, HP Storage
Krishna Sankavaran, Director for Research Information Systems & Technology Development, MD Anderson Cancer Center

 

Sponsored by
12:15 pm CycleCloud: Boosting Productivity with HPC as a Service on the Cloud
Jason Stowe, Chief Executive Officer, Cycle Computing
Now/Next generation Sequencers, spectrometers, and other medical instruments give scientists access to larger amounts of data at cheaper costs.  The cloud offers easy, inexpensive access to computing for sequence alignment, SNP detection, proteomics, and other scientific pipelines. For researchers that rely on computation to analyze these data sets, cloud computing can change the way science gets done by making it faster and more cost effective.
But successfully deploying applications to use the cloud efficiently involves a number of technical challenges. These include making applications scale, securing the clusters, and focusing on ease of use. CycleCloud makes this easy by pre-engineering clusters/pipelines to work optimally and securely on the Cloud.
With a focus on improving researcher productivity, CycleCloud creates fully-managed HPC clusters as a service with key applications pre-installed, the ability to quickly develop new analysis workflows, shared filesystems, and auto-scaling to size clusters to the multi-user workloads you place on them. This session will focus on:
• Bandwidth/data considerations for using the Cloud
• Productivity, ease of use, and security requirements
• Example walkthroughs of pre-engineered pipelines for drug discovery with Schrodinger, proteomics, and genome analysis use cases

12:30 Luncheon in the Exhibit Hall
***Drop off your business card at the CHI Sales Booth for a chance to win 1 of 2 Prizes! (Nintendo® Wii™ System or Apple® - iPod touch®)  Winners will be announced at 1:45pm in the Exhibit Hall

2:00 Exhibit Hall Closes

 

Data Storage and Usage for
CompuTational TASKS

1:55 Track Chairperson’s Remarks 

Ercan Kamber, Ph.D., Director HPC Engineering, RAID, Inc. 

 

2:00 Elastic-R, Toward an International Portal for On-Demand Scientific Computing, Collaboration and Resources Sharing

Karim Chine, Software Architect and Coordinator, Biocep

Elastic-R is a new portal built using the Biocep-R platform. It enables life scientists to use cloud resources seamlessly; to work with virtual scientific computing environments such as R and Scilab within the browser; to collaborate, share and reuse functions, algorithms, user interfaces, and servers; and to perform elastic distributed computing with any number of virtual machines to solve heavily computational problems. This talk will show the new Elastic-R portal in production and present the first results of that next experience

2:30 Making Systems and Services Easy: Secure File Sharing and Computational Portals

Shawn Houston, Technical Lead, Life Science Informatics, University of Alaska Fairbanks

Life Science Informatics at the University of Alaska Fairbanks provides a secure file share and a web based computational portal as interfaces to storage and computational resources. The two complimentary services are designed for ease of use, global access, and to foster research collaborations. Learn how our secure file shares and computational portal are designed with scientific research as their primary drivers.

3:00 Talk title to be Announced

4:00 Conference Adjourns

Apple® - iPod touch®,  Nano®, Nintendo® Wii™, are  not sponsors or participants in this program.