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Track 8: eHealth Solutions for Personalized Medicine

 

Final Agenda:

Track 8 explores the integration of life sciences, IT and general healthcare to support the care delivery process and innovative R&D of next generation health IT and personalized medicine solutions. Themes covered include EHRs and their impact on R&D, translational medicine, the development of companion diagnostics, integrating clinical data with genomic data, and technology tools to support the care delivery process.

TUESDAY, APRIL 12

7:00 am Workshop Registration and Morning Coffee

8:00 - 4:00 pm Pre-Conference Workshops*

*Separate Registration Required.

2:00 - 6:00 Main Conference Registration

4:00 Event Chairperson’s Opening Remarks

Cindy Crowninshield, RD, LDN, Conference Director, Cambridge Healthtech Institute

Sponsored by
Isilon Systems
4:05 Keynote Introduction

Chris Blessington, Life Sciences Solutions Architect, Isilon




Plenary Keynote

4:15 Making the World’s Knowledge Computable

StephenWolframStephen Wolfram, Ph.D., CEO, Wolfram Research; Creator of Wolfram|Alpha

 

 

 

Sponsored by
BlueARC-125px

5:00 Welcome Reception in the Exhibit Hall and Poster Viewing


 

 

 

Wednesday, April 13

7:00 am Registration and Morning Coffee

8:00 Event Chairperson’s Opening Remarks

Phillips Kuhl, Co-Founder and President, Cambridge Healthtech Institute

Sponsored by
TessellaNEW 
8:05 Keynote Introduction
Grant Stephen, CEO, Tessella, Inc.



Plenary Keynote

8:15 Interacting with Complex Information Landscapes: Integration and Next Generation User Interfaces

Bryn RobertsBryn Roberts, Ph.D., Global Head, Informatics, Pharma Research and Early Development, F. Hoffmann-La Roche Ltd.

 

 

 

 

8:45 Benjamin Franklin Award/Presentation: Jonathan Eisen, Ph.D., Professor, Genome Center, University of California, Davis

9:10 Best Practices Awards Program

Sponsored by
Scynexis

9:45 Coffee Break in the Exhibit Hall and Poster Viewing



 

 DELIVERING CLINICALLY ACTIONABLE
DATA TO THE PHYSICIAN AND BACK

Sponsored by
HP Small Logo
10:50 Chairperson’s Remarks

David Medina, Worldwide Life Science and Pharma Segment Executive, HP Enterprise Business






11:00 Connecting Patients, Providers and Payers

John D. Halamka, M.D., M.S., CIO, Harvard Medical School; CIO, Beth Israel Deaconess Medical Center; CIO, Harvard Clinical Research Institute

Patient engagement provisions in recent federal regulations are encouraging patients to collect and manage their own healthcare data from clinicians offices, personal health records, and home devices. In this presentation, we’ll examine the emergence of novel patient sourced data sources and their implications for research and clinical trials.

11:30 ATHENA Breast Health Network: A Model Learning System to Improve Clinical Care and Research

Subha Madhavan, M.D., Director, Clinical Research Informatics, Oncology, Georgetown University

The ATHENA Breast Health Network (ATHENA) is a unique collaboration among the five University of California (UC) medical centers that will revolutionize the delivery of care by integrating research and clinical care in prevention, screening, treatment and management of breast cancer. Critical to the success of this program is a technology roadmap that is adapting and extending current open source and commercial tools to collect, aggregate and report patient reported data, point-of-care clinical data, pathologic and molecular data, and clinical decisions, and provide the engine for comparative effectiveness and integration of optimal practices into clinical care.

Sponsored by
HP Small Logo
12:00 pm “Seeded” Cloud Computing Transformation in Cancer Research– A Case Study

Krishna Sankhavaram, Director, Research IS & Technology Development, University of Texas, MD Anderson Cancer Center

Srikanth Venkata Seshu, Worldwide Solutions Marketing Manager, HP StorageWorks

Learn how MD Anderson has strategically built one of the largest supercomputing centers of its kind in an academic research setting to service several next-generation sequencing laboratories in a centralized and virtualized private cloud environment.

12:30 Luncheon Presentation (Sponsorship Opportunity Available) or Lunch on Your Own

1:40 Chairperson’s Remarks

Samuel J. Aronson, Executive Director, IT, Harvard Medical School & Partners Healthcare for Genetics and Genomics

1:45 Delivering Scalable IT Support to Clinicians Practicing Personalized Medicine (60 min session)

Samuel J. Aronson, Executive Director, IT, Harvard Medical School & Partners Healthcare for Genetics and Genomics

Heidi Rehm, Ph.D., FACMG, Laboratory Director, Molecular Medicine, Assistant Professor of Pathology, Harvard Medical School

The value of personalized medicine rests on enabling clinicians to use genetics to make better decisions. In practice, as genetic testing becomes more complex and widespread, it will become increasingly difficult for clinicians to track which variants have been found in each of their patients and how these variants should impact the clinical decisions they make. Information technology can help solve this problem, but to be effective applications must enable new forms of integration between laboratories and treating clinicians. In effect, genetic testing laboratories, clinical end users and IT need to work together to create support for new clinical processes and workflows that cannot exist without substantial IT support. In this presentation, we will discuss our experience designing, building and deploying these types of applications.

2:45 Enabling Secondary Uses of EMR: The Quality Stack

Gary Keith Mallow, Ph.D., Director, Health Information Technology, Merck & Co., Inc.

3:15 Refreshment Break in the Exhibit Hall and Poster Viewing

3:45 Synergistic Patient and Research Knowledge Systems—An Enterprise Data Integration and Analysis Platform

Jomol Mathew, Ph.D., Director, Clinical and Translational Informatics, IS, Dana-Farber Cancer Institute

The Synergistic Patient and Research Knowledge System (SPARKS) establishes an enterprise informatics framework designed to accelerate scientific discoveries, and their translation into personalized medicine and clinical practice. SPARKS implements the policies, standards, systems, and tools that facilitate the collection, integration, mining, analysis, and interpretation of biomedical data.

4:15 Exploring Risk/Benefit Profiles of Medicines through Mining of Observational Data

Victor Lobanov, Director, Informatics & Pharmaceutical R&D, Johnson & Johnson Pharmaceutical

Observational healthcare databases, such as administrative claims and electronic health records, offer a wealth of information for analysis of natural history of diseases, effectiveness of treatments, safety profiles of medications, and drug utilization trends. Several open-source analytics tools to perform such analyses have been created and are under investigation as part of the Observational Medical Outcomes Partnership, a public-private partnership between the pharmaceutical industry, academic institutions, non-profit organizations, and federal agencies. At Johnson & Johnson Pharmaceutical Research & Development we have developed an efficient infrastructure to manage licensed commercial healthcare databases and a systematic approach to apply observational analyses across multiple data sources to support our portfolio of medical products.

4:45 Why Actions Speak Louder than Words: Early Case Studies in Personalized Medicine

Tibor van Rooij, Ph.D. Candidate, Pharmacy and Pharmaceutical Sciences, University of Alberta; former Director of Bioinformatics, Génome Québec and Montreal Heart Institute Pharmacogenomics Centre

Although validated and approved genomics-based tests are available for targeted therapeutics, a major challenge facing healthcare is the ability to process the genomic data in the patient’s context and to return clinically interpretable dosing guidance to the physician in a realistic time frame. The realization of targeted therapeutics will depend on case studies to prove the effect of concerted efforts of multi-disciplinary teams as they address political, ethical, socio-economical and IT challenges to achieve personalized medicine adoption through real-world implementation. We review early personalized medicine case studies, their delivery mechanism and the impact of using targeted therapeutics. In capturing the outcomes data, these case studies are demonstrating both the feasibility and cost-effectiveness of the real-world application of personalized medicine.

5:15 Best of Show Awards in the Exhibit Hall

6:15 Exhibit Hall Closes

 

Thursday, April 14

8:45 Event Chairperson’s Opening Remarks

Kevin Davies, Ph.D., Editor-in-Chief, Bio-IT World

8:50 KEYNOTE PANEL:
Sponsored by
BT
Keynote Introduction
A special plenary session featuring a series of succinct, forward-looking presentations by:

Ken Buetow, Ph.D., Associate Director, Bioinformatics and Information Technology, National Cancer Institute

Debra Goldfarb, Senior Director, Strategy, Microsoft

Martin D. Leach, Ph.D., Executive Director, MRL IT for Discovery & Pre-Clinical Sciences, Merck & Co.

Mark Boguski, M.D., Ph.D., Founder, Resounding Health Incorporated

Jamie Heywood, Co-founder and Chairman, PatientsLikeMe
Yury Rozenman, Global Head of Marketing, Pharmaceutical and Life Sciences Sector, BT Global Services

10:30 Coffee Break in the Exhibit Hall with Poster Competition

 

 HEALTHCARE INFORMATICS AND
PERSONALIZED MEDICINE FROM
THE PHARMACEUTICAL PERSPECTIVE

10:55 Chairperson’s Remarks

David Leventhal, Director, Healthcare Informatics, Pfizer

11:00 eHealth: A Transformative Opportunity for Pharma

Chris L. Waller, Ph.D., Senior Director, HealthCare Informatics, Medical Business Technology, Pfizer, Inc.

Advances in health information technology (HIT) present the pharmaceutical industry with many innovative opportunities that promise to transform business processes across the research, development, commercial, and medical continuum. For over a decade, Pfizer has recognized the potential of, and supported advances in, HIT. At Pfizer, a cross-disciplinary eHealth team comprising representatives from Corporate Strategy and Innovation, Business Technology, Business Development, and Policy has been created to identify, evaluate, and implement HIT-enabled business changes. The team is focused on opportunities to expand and diversify Pfizer’s commercial offerings through expansion of our consumer and provider healthcare products and services business. Consumer electronics, remote health monitoring, and health and wellness services are all being actively explored. A second broad area of interest lies in the secondary uses of clinical and healthcare data space. Electronic medical record systems, clinical decision support, adverse event reporting, and health economics analytics advances all pose disruptive innovation opportunities for the industry as a whole.

11:30 Using HIT Health IT to Breakdown Geographic and Social Barriers and Advance Personalized Medicine and Drug R&D

Eric D. Perakslis, Ph.D., Vice President, Research & Development IT, Johnson & Johnson Pharmaceuticals Research and Development

Despite years of technological progress and an unprecedented push for EMRs via government stimulus, few successful examples of eHealth business models exist. The basic abilities to reach wider patient audiences, aggregate medical data, identify patient populations at need/risk and to provide a healthcare collaboration platform across public, private and NGO boundaries are within reach and must be realized.

12:00 Healthcare Technologies to Enable Health@Home

Adel Laoui, Ph.D., M.B.A., Director, Healthcare Technologies, Aging Therapeutic Strategic Unit, Sanofi-Aventis U.S.

This presentation will address the new opportunities arising for the aging business. A fantastic mission to address the aging challenges is ahead of a stressed society forced to reduce healthcare cost and improve the quality of life of patients and caregivers.  The scope ranges from solutions for drug administration to ensure treatment adherence to diagnostics & labs ‘@ home’ to minimize travel to the medical facility, to telemedicine for prevention and to ‘smart homes’ integrating all these technologies. All of these needed healthcare technology solutions requires an unprecedented effort to consolidated a much segmented market and develop a vision of a true integrated and diversified healthcare system.

12:30 Luncheon in the Exhibit Hall and Poster Viewing

2:00 Exhibit Hall Closes

 

 CASE STUDIES IN HIT AND eCLINICAL
FROM THE caBIG PERSPECTIVE

Solutions for Personalized Medicine and eClinical Solutions
(shared session between tracks 7 and 8)

1:55 Chairperson’s Remarks

Presented by
caBIG sm
2:00 Creating a Research Infrastructure to Support Cancer Personalized Medicine

Gregory C. Bloom, Ph.D., Assistant Professor, Biomedical Informatics, H. Lee Moffitt Cancer Center and Research Institute

Sorena Nadaf, Director, Translational and Biomedical Informatics and CIO, Helen Diller Family Comprehensive Cancer Center Translational Informatics, University of California, San Francisco

Kenneth Buetow, Ph.D., Associate Director for Bioinformatics and Information Technology, National Cancer Institute

The personalized medicine paradigm requires data liquidity so that information and knowledge can be freely exchanged among stakeholders at all stages of the bench-to-bedside continuum. In this approach to biomedicine, research and clinical care are seamlessly linked in a virtuous circle that enables the collection and analysis of information on clinical outcomes of large populations. This session will discuss how caBIG® technology is being leveraged to build and extend capabilities that will support a rapid learning system of healthcare.

USING HEATH RECORDS AND POINT-OF-CARE DATA TO ACCELERATE PATIENT RECRUITMENT

3:00 Interactive Presentations and Panel Discussion

The Partnership to Advance Clinical electronic Research (PACeR) is a broad-based health care collaborative that is led by the Healthcare Association of New York and comprised of New York State hospitals, healthcare providers, patients and pharmaceutical and technology companies. Since its inception in early 2010, PACeR has been working to identify new approaches for the collection and use of clinical information to accelerate evidence-based medical research. Its long-range goal is to improve the delivery and outcomes of patient care by effectively and efficiently leveraging electronic clinical data for research-related activities through a sustainable model.
Key goals of this broad public-private participation are to:

  • Support improvements in patient care and facilitate the research missions of participating institutions
  • Promote large-scale integrated electronic health capability across multiple institutions and organizations
  • Assist medical institutions to meet their objectives regarding the primary and secondary use of clinical data
  • Accomplish these objectives in a way that is economically sustainable; and serve as a viable, practical model for other states and regions that takes into account
  • Resolves relevant legal, regulatory, economic, and operational issues

David A. Krusch, M.D., Chief Medical Information Officer, University of Rochester Medical Center

Terri Straub, Consultant, Healthcare Association of New York State
David Leventhal, Director, Healthcare Informatics, Pfizer

Jeff Kraut, Senior Vice President, Strategic Planning and Marketing, North Shore-LIJ Health System

John Murphy, Dr.P.H., Head, Clinical Analytics, Quintiles

4:00 Conference Adjourns



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